DRC may refer to:
The Democratic Republic of the Congo, a country located in Central Africa.
European humanitarianismDanish Refugee Council, private Danish humanitarian organisationDisability Rights Commission, independent non-departmental public body set up by the British Parliament to end discrimination against disabled people
TechnologyDesktop replacement computer, a personal computer that provides the full capabilities of a desktop computer while remaining mobileDRC railcar, a diesel-powered self-propelled railway vehicle in Victoria, AustraliaDesign rule checking, area of Electronic Design Automation that determines if a chip design satisfies a series of parametersDigital room correction, process in the field of acoustics using digital filters to enhance the input of a sound-reproduction systemDisaster Recovery Center, a facility for operating with backup equipment and/or dataDynamic range compression, process that manipulates the dynamic range of an audio signalDynamic Reaction Cell, room placed before the traditional quadrupole room of an ICP-MS device for eliminating isobaric interferencesDynamic recompilation, technique of translating the machine code of one CPU or platform into the native machine code of another for emulationDARPA Robotics Challenge
OtherDictatorship Resistance CommitteeThe Challoner revision of the Douay-Rheims BibleDanang Rubber Company, a Vietnam tire companyDartford River Crossing, a major road-transport crossing of the River Thames in EnglandDetonautas Roque Clube, a Brazilian rock-bandDemocratic Representative Caucus, a group of Canadian Members of Parliament who left the Canadian Alliance in 2001 in protest against the leadership of Stockwell DayDemocratic Resettlement Community, an informal settlement in Swakopmund, NamibiaThe Disaster Research Center, or DRC, a U.S. organization devoted to the study of disastersDomain relational calculus, calculus introduced by Michel Lacroix and Alain Pirotte as a declarative database query language for the relational data modelDomaine de la Romanée-Conti, wine producer of Burgundy, FranceDr. Regis Chaperon State Secondary School, a secondary school in MauritiusDynamics Research Corporation, a United States-based publicly held defense contractorDutch Reformed Church, or Nederlandse Hervormde Kerk, a Christian denomination in the NetherlandsNederduits Gereformeerde Kerk, (English: "Dutch Reformed Church") in South AfricaD'ni Restoration Council, fictional organization of the universe of computer game MystDirico Airport, airport in Angola with IATA code DRC
PeopleDominique Rodgers-Cromartie, an American football player